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Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos |
| Phenotype | phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (CANONICAL) |
| Enrichment Score (ES) | -0.6812614 |
| Normalized Enrichment Score (NES) | -1.6864601 |
| Nominal p-value | 0.006369427 |
| FDR q-value | 0.13130575 |
| FWER p-Value | 0.79 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | FZD5 | 1422937_at 1430809_at | 2087 | 0.610 | -0.0693 | No | ||
| 2 | APC | 1420956_at 1420957_at 1435543_at 1450056_at | 2267 | 0.562 | -0.0536 | No | ||
| 3 | CTNNBIP1 | 1417567_at 1431694_a_at | 2346 | 0.542 | -0.0341 | No | ||
| 4 | FZD7 | 1450043_at 1450044_at | 2710 | 0.466 | -0.0308 | No | ||
| 5 | FZD4 | 1419301_at 1449416_at | 4005 | 0.308 | -0.0768 | No | ||
| 6 | PYGO1 | 1431091_at | 4587 | 0.272 | -0.0918 | No | ||
| 7 | FZD1 | 1422985_at 1437284_at | 5631 | 0.226 | -0.1298 | No | ||
| 8 | YWHAB | 1420878_a_at 1420879_a_at 1420880_a_at 1436783_x_at 1438708_x_at 1455815_a_at | 6981 | 0.179 | -0.1838 | No | ||
| 9 | DVL3 | 1420457_at | 7038 | 0.177 | -0.1788 | No | ||
| 10 | NLK | 1419112_at 1435970_at 1443279_at 1445427_at 1456467_s_at | 7740 | 0.156 | -0.2042 | No | ||
| 11 | CTNNB1 | 1420811_a_at 1430533_a_at 1450008_a_at | 7984 | 0.149 | -0.2089 | No | ||
| 12 | DVL2 | 1417207_at 1448616_at | 8063 | 0.147 | -0.2062 | No | ||
| 13 | TCF3 | 1436207_at 1450117_at | 10063 | 0.098 | -0.2933 | No | ||
| 14 | FZD3 | 1420087_at 1421157_at 1438101_at 1449730_s_at 1450135_at | 10999 | 0.076 | -0.3327 | No | ||
| 15 | FZD8 | 1423348_at 1445815_at | 12840 | 0.033 | -0.4153 | No | ||
| 16 | FZD6 | 1417301_at 1448662_at 1458904_at | 14563 | -0.016 | -0.4933 | No | ||
| 17 | FZD2 | 1418532_at 1418533_s_at | 15805 | -0.061 | -0.5473 | No | ||
| 18 | FZD9 | 1427529_at | 16134 | -0.077 | -0.5590 | No | ||
| 19 | SFN | 1448612_at | 17471 | -0.178 | -0.6124 | No | ||
| 20 | YWHAE | 1426384_a_at 1426385_x_at 1435702_s_at 1438839_a_at 1440841_at 1457173_at | 17505 | -0.181 | -0.6063 | No | ||
| 21 | DVL1 | 1437301_a_at 1450978_at | 17620 | -0.192 | -0.6033 | No | ||
| 22 | AXIN1 | 1426966_at 1426967_at 1441029_at | 17643 | -0.197 | -0.5959 | No | ||
| 23 | TCF7 | 1433471_at 1450461_at | 17685 | -0.200 | -0.5893 | No | ||
| 24 | TCF7L2 | 1425229_a_at 1426639_a_at 1429427_s_at 1429428_at 1441756_at 1446452_at 1447071_at | 19700 | -0.564 | -0.6573 | Yes | ||
| 25 | LEF1 | 1421299_a_at 1436398_at 1440760_at | 19824 | -0.603 | -0.6372 | Yes | ||
| 26 | YWHAG | 1420816_at 1420817_at 1450012_x_at 1459693_x_at | 19896 | -0.621 | -0.6141 | Yes | ||
| 27 | FRAT2 | 1455220_at | 20292 | -0.777 | -0.5991 | Yes | ||
| 28 | BCL9 | 1445859_at 1446767_at 1451574_at 1455565_at | 21332 | -1.670 | -0.5755 | Yes | ||
| 29 | AXIN2 | 1421341_at 1436845_at | 21578 | -2.212 | -0.4926 | Yes | ||
| 30 | SMAD4 | 1422485_at 1422486_a_at 1422487_at 1444205_at | 21604 | -2.282 | -0.3967 | Yes | ||
| 31 | CSNK1E | 1417175_at 1417176_at 1435373_at | 21762 | -2.918 | -0.2797 | Yes | ||
| 32 | GSK3B | 1434439_at 1437001_at 1439931_at 1439949_at 1451020_at 1454958_at | 21817 | -3.254 | -0.1438 | Yes | ||
| 33 | CREBBP | 1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at | 21856 | -3.508 | 0.0037 | Yes |
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